A new labdane diterpene from Rauvolfia tetraphylla Linn. (Apocynaceae)
Rauvolfia tetraphylla Linn. (syn. R. canescens L., family: Apocynaceae) holds an important position in the Indian traditional system of medicine, and has other immense applications. This particular plant is regarded as a rich source of a wide variety of important alkaloid constituents such as reserpine, reserpiline, raujemidine, isoreserpiline, deserpidine, aricine, ajmaline, ajmalicine, yohimbines, serpentine, sarpagine, vellosimine and tetrphylline. However, there is no report on the terpenoid constituent from this plant, and we report the isolation from the air-dried stems and branches of R. tetraphylla and structural elucidation of a new labdane diterpene, 3-hydroxy-labda-8(17),13(14)-dien-12(15)-olide (1; Fig. 1) bearing an unusual -lactone moiety.
Fig. 1 Structure of labdane diterpene
Goutam Brahmachari*, Lalan Ch. Mandal, Dilip Gorai, Avijit Mondal, Sajal Sarkar and Sasadhar Majhi
Doi: 10.3184/174751911X13220462651507
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