Barcelona, Spain (Scicasts)
Baringolin is a marine product with antibiotic properties. Image: IRB Barcelona
– Bacterial resistance
to drugs leads pharmaceutical labs to be in constant search for new
antibiotics to treat the same diseases. For the last thirty years, the
sea bottom has yielded a wealth of substances with properties of
interest to the pharmaceutical industry.
Isolated from a marine microorganism off the coast of Alicante by the
company BioMar, baringolin shows promising antibiotic activity at a
very low concentration. The Combinatorial Lab headed by Fernando
Albericio at the Institute for Research in Biomedicine (IRB Barcelona),
which collaborates with BioMar, has now synthesized this molecule and
revealed its structure. Today's results open up the possibility to
better understand how this substance works and to design derivatives to
turn into a viable drug in the next 10 years. These findings are
published in todays' online edition of the journal Angewandte Chemie.
read all at
From left to right, this image shows researchers Mercedes Alvárez,
Xavier Just-Baringo and Fernando Albericio from the IRB Barcelona.
(Photo Credit: IRB Barcelona)