Iodine-mediated arylation of benzoxazoles with aldehydes

A simple and efficient methodology for the arylation of benzoxazoles with aldehydes using iodine as the mediator has been developed. The reaction proceeded smoothly with a range of substrates to give the corresponding arylated products in moderate to good yields

Green Chem., 2013, 15,2365-2368
DOI: 10.1039/C3GC41027G, Communication

Yew Chin Teo,^a   Siti Nurhanna Riduan^a and   Yugen Zhang*^a

*

Corresponding authors

^a

Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore
E-mail: ygzhang@ibn.a-star.edu.sg ;
Fax: (+65) 6478-9020

A simple and efficient methodology for the arylation of benzoxazoles with aldehydes using iodine as the mediator has been developed

PRINS REACTION

PRINS REACTION

Explosive Nanotechnology

A team of American scientists have developed highly reactive nanoenergetic formulations based on periodate salts

Read more

Multiple Metal-Free Pathways to 2-Acyloxazoles

2-Acyloxazoles can be formed from a variety of different starting materials just by tweaking the iodine oxidant

Read more

Multiple Metal-Free Pathways to 2-Acyloxazoles

Resolving Asymmetric Epoxidations

An enantioselective route to form epoxides by using kinetic resolution techniques has been developed

Read more

Research Suggests Fatty Acids Could Aid Cancer Prevention and Treatment « New Drug Approvals

Research Suggests Fatty Acids Could Aid Cancer Prevention and Treatment « New Drug Approvals:

'via Blog this'

A method for the synthesis of α-amino acids by direct reductive carboxylation of aromatic imines with CO₂ is described. The protocol employs readily available commercial reagents and serves as a one-step alternative to the Strecker synthesis.

A synthesis of α-amino acids via direct reductive carboxylation of imines with carbon dioxide

Ajay A. Sathe,^a   Douglas R. Hartline^a and  Alexander T. Radosevich*^a  

* Corresponding authors

^a

Department of Chemistry, The Pennsylvania State University, University Park, USA 
E-mail: radosevich@psu.edu ;
Tel: +1 814 867 4268

Chem. Commun., 2013,49, 5040-5042

DOI: 10.1039/C3CC42057D
Received 21 Mar 2013, Accepted 16 Apr 2013
First published online 25 Apr 2013

http://pubs.rsc.org/en/content/articlelanding/2013/CC/c3cc42057d