DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God
DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 30 Yrs Exp. in the feld of Organic Chemistry. Serving chemists around the world. Helping them with websites on Chemistry.Millions of hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution
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Showing posts with label ORGANIC CHEMISTRY. Show all posts
Showing posts with label ORGANIC CHEMISTRY. Show all posts

Thursday 27 June 2013

A molecular database for developing organic solar cells


molecular_space_logo




Harvard researchers have released a massive database of more than 2 million molecules that might be useful in the construction of solar cells that rely on organic compounds for construction of organic solar cells for the production of renewable energy. Developed as part of the Materials Genome Initiative launched by the White House’s Office of … more…

http://www.kurzweilai.net/a-molecular-database-for-developing-organic-solar-cells?utm_source=KurzweilAI+Daily+Newsletter&utm_campaign=4fc1bf53a4-UA-946742-1&utm_medium=email&utm_term=0_6de721fb33-4fc1bf53a4-282116853





Monday 24 June 2013

Lab Reproduction of Marine Compound with Antibiotic Properties




 
Baringolin is a marine product with antibiotic properties. Image: IRB Barcelona
 

Barcelona, Spain (Scicasts) – Bacterial resistance to drugs leads pharmaceutical labs to be in constant search for new antibiotics to treat the same diseases. For the last thirty years, the sea bottom has yielded a wealth of substances with properties of interest to the pharmaceutical industry.
 
Isolated from a marine microorganism off the coast of Alicante by the company BioMar, baringolin shows promising antibiotic activity at a very low concentration. The Combinatorial Lab headed by Fernando Albericio at the Institute for Research in Biomedicine (IRB Barcelona), which collaborates with BioMar, has now synthesized this molecule and revealed its structure. Today's results open up the possibility to better understand how this substance works and to design derivatives to turn into a viable drug in the next 10 years. These findings are published in todays' online edition of the journal Angewandte Chemie.

read all at

http://scicasts.com/bioit/1858-drug-development/6186-lab-reproduction-of-marine-compound-with-antibiotic-properties

From left to right, this image shows researchers Mercedes Alvárez, Xavier Just-Baringo and Fernando Albericio from the IRB Barcelona.
(Photo Credit: IRB Barcelona)


/files/Image/XavierJust.jpg

Xavier Just, PhD student at IRB Barcelona, has reproduced the natural structure in the lab

 Reference article:
Total Synthesis and Stereochemical Assignment of Baringolin
Xavier Just-Baringo, Paolo Bruno, Lars K. Ottesen, Librada M. Cañedo, Fernando Albericio and Mercedes Álvarez.
Angewandte Chemie (2013) http://dx.doi.org/10.1002/ange.201302372 (German Edition) http://dx.doi.org/10.1002/anie.201302372 (International Edition)



Natural Products from St. John's Wort


Natural Products from St. John's Wort

Enatiomers (−)-hyperione A and (−)-hyperione B can be synthesised from a common precursor in ten steps
Read more


http://www.chemistryviews.org/details/ezine/1238795/Natural_Products_from_St__Johns_Wort.html



doc b's CV

Tuesday 11 June 2013

Bruce Roth Awarded 2013 Perkin Medal


Bruce Roth
Roth
Credit: Genentech

Bruce Roth Awarded 2013 Perkin Medal

Honors: Chemist was the first to synthesize the cholesterol-lowering drug atorvastatin, also known as Lipitor
The Society of Chemical Industry (SCI) has selected Bruce D. Roth, vice president of discovery chemistry at Genentech, as the winner of the 2013 Perkin Medal. The annual award is recognized as the highest honor given for outstanding work in applied chemistry in the U.S.
http://cen.acs.org/articles/91/web/2013/06/Bruce-Roth-Awarded-2013-Perkin.html




A Molecule Of Many Colors-With rigid wings and a flexible core, a new compound can switch between two shapes and glow one of three colors.


Structure of a flexible molecule in its flat and bent shapes
 
Flexible And Fluorescent
A molecule combining rigid anthraceneimide wings and a flexible cyclooctatetraene core switches between a flat and a bent V shape. The R groups are either hydrogens or n-butyl groups.
Credit: J. Am. Chem. Soc.

A Molecule Of Many Colors

Organic Chemistry: With rigid wings and a flexible core, a new compound can switch between two shapes and glow one of three colors.

A new, flexible, multi-ring organic compound fluoresces red, green, or blue depending on its environment (J. Am. Chem. Soc. 2013, DOI: 10.1021/ja404198h). The molecule’s combination of rigid wings and a flexible center could serve as a general design strategy for molecular sensors, the researchers say.
The molecule, developed by a team of researchers, including Shohei Saito, Stephan Irle, and Shigehiro Yamaguchi of Nagoya University in Japan, has two rigid anthraceneimide wings on opposite sides of a floppy cyclooctatetraene core

read all at
http://cen.acs.org/articles/91/web/2013/06/Molecule-Colors.html

Monday 10 June 2013

ORGANIC CHEMISTRY REACTIONS, website by DR ANTHONY CRASTO

 

CLICK ON LINK BELOW
https://sites.google.com/site/anthonycrastoreactions/home

CLICK ON LINK ABOVE



Friday 31 May 2013

Exploiting Structural Differences in Serotonin Receptors


Exploiting Structural Differences in Serotonin Receptors



Serotonin receptors present structural differences which can be used to design agonistic drugs devoid of side effects
Read more
 

Friday 17 May 2013

New Drug May Help Immune System Fight Cancer


May 16, 2013 — An experimental drug that taps the power of the body’s immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.
read all at

Saturday 12 May 2012

Whats new in Chemistry

READ ALL THIS AT
http://amcrasto.biz.ly/whats_new.html



Scientists discover chemistry of passion




Scientists say there is increase in the levels of hormones neutrophins and dopamine when cupid strikes.
LONDON, UNITED KINGDOM: Couples should not worry when the first flush of passion dims - scientists have identified the hormone changes which cause the switch from lust to cuddles. A team from the University of Pisa in Italy found the bodily chemistry which makes people sexually attractive to new partners lasts, at most, two years. When couples move into a “stable relationship” phase, other hormones take over, Chemistry World reports.



  




LOVE, actually is chemicals racing internally







Scientists say there is increase in levels of hormones neutrophins and dopamine when cupid strikes.
When couples fall in love, outwardly they experience dizziness, flushed face, sweaty palms and most prominent of all a wildly beating heart. But, internally, the feeling of love is due to chemicals racing around the brain and body.
The feelings, researchers found are due to dopamine, norepinephrine and phenylethylamine that human beings release. Dopamine is thought to be the “pleasure chemical,” producing a feeling of bliss. Norepinephrine is similar to adrenaline and produces the racing heart and excitement. Together these two chemicals produce elation, intense energy, sleeplessness, craving, loss of appetite and focused attention, discovered Helen Fisher, anthropologist at Rutgers University. “The human body releases the cocktail of love rapture only when certain conditions are met. And men more readily produce it than women, because of their more visual nature,” she added.