SYNTHESIS OF INDOLES

http://onlinelibrary.wiley.com/doi/10.1002/anie.201203657/abstract

Synthesis of Indoles 

Synthesis of Indoles through Highly Efficient Cascade Reactions of Sulfur Ylides and N-(ortho-Chloromethyl)aryl Amides 

Qing-Qing Yang, ET AL

DOI: 10.1002/anie.201203657

A simple procedure carried out under mild conditions allows the direct and efficient synthesis of structurally diverse indoles. This approach involves a cascade reaction of sulfur ylides and N-(ortho-chloromethyl)aryl amides (see scheme).