Cheap nickel catalysis offers alternative to expensive enzymatic resolution, Switching chirality in amino acids

Amino acids are converted to their opposite enantiomers by complexation with a nickel(II) salt and a chiral ligand Switching chirality in amino acids
	Cheap nickel catalysis offers alternative to expensive enzymatic resolution http://www.rsc.org/chemistryworld/2013/06/switching-chirality-amino-acids-nickel-catalysis

Improved R&D Efficiency Through Speedier Method Development (1)

Improved R&D Efficiency Through Speedier Method Development (1)

Various approaches are available for improving the efficiency of analytical...

http://www.pharmaceutical-business-review.com/suppliers/shimadzu-analytical-instrumentation/whitepapers/improved-rd-efficiency-through-speedier-method-development-1

Strategic Approaches to Process Optimization and Scale-up

 
http://drug-scaleup-and-manufacturing.webnode.com/news/strategic-approaches-to-process-optimization-and-scale-up/

Bruce Roth Awarded 2013 Perkin Medal

Roth

Credit: Genentech

Bruce Roth Awarded 2013 Perkin Medal

Honors: Chemist was the first to synthesize the cholesterol-lowering drug atorvastatin, also known as Lipitor
The Society of Chemical Industry (SCI) has selected Bruce D. Roth, vice president of discovery chemistry at Genentech, as the winner of the 2013 Perkin Medal. The annual award is recognized as the highest honor given for outstanding work in applied chemistry in the U.S.
http://cen.acs.org/articles/91/web/2013/06/Bruce-Roth-Awarded-2013-Perkin.html

A Molecule Of Many Colors-With rigid wings and a flexible core, a new compound can switch between two shapes and glow one of three colors.

 

Flexible And Fluorescent

A molecule combining rigid anthraceneimide wings and a flexible cyclooctatetraene core switches between a flat and a bent V shape. The R groups are either hydrogens or n-butyl groups.

Credit: J. Am. Chem. Soc.

A Molecule Of Many Colors

Organic Chemistry: With rigid wings and a flexible core, a new compound can switch between two shapes and glow one of three colors.

A new, flexible, multi-ring organic compound fluoresces red, green, or blue depending on its environment (J. Am. Chem. Soc. 2013, DOI: 10.1021/ja404198h). The molecule’s combination of rigid wings and a flexible center could serve as a general design strategy for molecular sensors, the researchers say.

The molecule, developed by a team of researchers, including Shohei Saito, Stephan Irle, and Shigehiro Yamaguchi of Nagoya University in Japan, has two rigid anthraceneimide wings on opposite sides of a floppy cyclooctatetraene core

read all at
http://cen.acs.org/articles/91/web/2013/06/Molecule-Colors.html

ORGANIC CHEMISTRY REACTIONS, website by DR ANTHONY CRASTO

 

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DRUG SYNTHESIS PORTALS ON NET-A COLLECTION

READ ALL AT

http://newdrugapprovals.wordpress.com/drug-synthesis/
DRUG SYNTHESIS PORTALS ON NET-A COLLECTION