DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, This will not stop me
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Monday, 16 April 2012

Cucurbiturils , molecular container that can encapsulate drug molecules and increase the solubility of drugs

cucurbit[n]urils
Giving drug dropouts a new lease of life
Researchers in the US have designed a molecular container that can encapsulate drug molecules and increase their solubility - in one case by almost 3000 times. The new container appears to have low toxicity and can be built from readily available reagents. The finding opens the possibility of re-testing drug candidates that failed because they were insufficiently soluble or improving existing low-solubility drugs.


D Ma et alNat. Chem., 2012, DOI: 10.1038/nchem.1326 





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Wednesday, 4 April 2012

Monday, 2 April 2012

Imidazole derivatives: A comprehensive survey of their recognition properties


Imidazole derivatives: A comprehensive survey of their recognition properties

Pedro Molina ,  Alberto Tárraga and Francisco Otón

Affiliation Information

1. Departamento de Química Orgánica; Universidad de Murcia; Campus de Espinardo, , Spain

Org. Biomol. Chem., 2012, 10, 1711-1724

DOI:10.1039/C2OB06808G
Due to its amphoteric nature the imidazole ring can function as selective and effective anion and/or cation and even neutral organic molecules receptor system.
Graphical abstract: Imidazole derivatives: A comprehensive survey of their recognition properties